i think it depends on what you are photographing
as you will probably know with cropped sensors you will not get as much in the frame as you would with a full frame sensor which could be a bad thing for landscape and portrait photography
a cropped sensor can have advantages for wildlife photography where the part of the frame that is lost won't really count but this really depends on how close you are to your subject ( usually not that close )
full frame sensors tend to fair better in low light because the cell sites tend to be bigger allowing them to gather more light
the reality is if you can afford a decent full frame camera ( 5d mk11 for example ) then i would go for that rather than splashing out on a cropped sensor camera and wishing you had gone for a full frame
to sum up

dissadvatages of full frame = none ( well maybe price )
dissadvantages of cropped frame = landscape , portrait photography